COMPARISON EFFECTIVENESS OF MBSR AND CBT ON INTERLEUKIN 6 AND OXIDATIVE STRESS IN HYPERTENSIVE PATIENTS

Life Sciences-Psychology

Authors

  • BEHROOZ BIRASHK Associate Professor of Clinical psychology, Department of Clinical Psychology, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Science, Tehran, Iran
  • FARSHAD SHEYBANI Ph.D Candidate in clinical psychology, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Science, Tehran, Iran
  • BANAFSHEH GHARRAEE Associate Professor of Clinical psychology, Department of Clinical Psychology, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Science, Tehran, Iran
  • MOHAMADREZA PIRMORADI Assistant Professor of Clinical psychology, Department of Clinical Psychology, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Science, Tehran, Iran
  • SHOKOUFEH HAJSADEGHI Assistant Professor of Cardiology, Department of Cardiology, Rasoul-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran

DOI:

https://doi.org/10.22376/ijpbs/lpr.2018.8.3.L39-45

Keywords:

Hypertension; Interleukin 6; Oxidative Stress; Mindfulness-Based Stress Reduction; Cognitive- Behavioral Stress Management

Abstract

Cardiovascular diseases are the leading cause of death in developing countries. Research has shown that the level of oxidative stress and interleukin 6 (IL-6) is higher in individuals with hypertension than individuals with normal blood pressure. Therefore, the aim of the present randomized clinical trial study was to compare the effectiveness of mindfulness-based stress reduction (MBSR) and cognitive-behavioral therapy (CBT) on oxidative stress and interleukin 6. Sixty patients with primary hypertension were divided into two intervention groups (MBSR and CBT) and one control group. Oxidative stress and IL-6 were measured by prooxidant-antioxidant balance (PAB) and ELISA method (Biovendor kit), respectively. Data analysis was carried out using ANOVA and MANCOVA in SPSS Ver.19. The results showed that MBSR significantly reduced oxidative stress. Also, MBSR and CBT significantly reduced IL-6 levels.

Published

2022-06-18

How to Cite

BEHROOZ BIRASHK, FARSHAD SHEYBANI, BANAFSHEH GHARRAEE, MOHAMADREZA PIRMORADI, & SHOKOUFEH HAJSADEGHI. (2022). COMPARISON EFFECTIVENESS OF MBSR AND CBT ON INTERLEUKIN 6 AND OXIDATIVE STRESS IN HYPERTENSIVE PATIENTS: Life Sciences-Psychology. International Journal of Life Science and Pharma Research, 8(3), 39–45. https://doi.org/10.22376/ijpbs/lpr.2018.8.3.L39-45

Issue

Volume 8 Issue 3, July - September 2018

Section

Research Articles
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