CAPSAICIN AND GUT MOTILITY

Life Sciences-Physiology

Authors

  • SHUCHITA SINGH Department of Physiology Institute of Medical Science Banaras Hindu University, Varanasi- 221005
  • MALOY B. MANDAL Department of Physiology Institute of Medical Science Banaras Hindu University, Varanasi- 221005

Keywords:

Capsaicin, gut, motility, TRPV1.

Abstract

Capsaicin is one of the most important capsaicinoids and forms the main pungent ingredient of chili peppers. It is known to release biologically active substances which affect motility of gut in different species. In human, capsaicin  has been  shown  to alter  gastric  emptying  time  and capsaicin  receptors  have been  implicated  in irritable bowel syndrome (IBS). Capsaicin, acts through capsaicin receptor, Transient receptor potential subtype 1 (TRPV1). Capsaicin receptor immunoreactivity has been also reported in different parts of the gut in different mammalian species. Studies indicated that capsaicin mediate its effect by releasing endogenous substances like tachykinins,  calcitonin  gene  related  peptide  (CGRP)  and  other  substances  in  gut.  The  present  review concentrates on effect of capsaicin on gut motility.

Published

2022-06-18

How to Cite

SHUCHITA SINGH, & MALOY B. MANDAL. (2022). CAPSAICIN AND GUT MOTILITY: Life Sciences-Physiology. International Journal of Life Science and Pharma Research, 5(2), 46–53. Retrieved from https://ijlpr.com/index.php/journal/article/view/451

Issue

Volume 5 Issue 2, April - June 2015

Section

Research Articles
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