SYNTHESIS AND ANTI-MICROBIAL STUDY OF OXADIAZOLYL INDAZOLES

Life Science-Organic Chemistry

Authors

  • RAVIRAJ A KUSANUR Department of chemistry, R V College of Engineering, R V Vidyanikethana Post Mysore Road Bangalore
  • MAHESH R Department of chemistry, R V College of Engineering, R V Vidyanikethana Post Mysore Road Bangalore

Keywords:

3-Aminoindazole, Suzuki reaction, Oxadiazoles, anti-microbial activity

Abstract

A rapid and efficient synthesis of substituted N-[(1,3,4-oxadiazol-2-yl)methyl]-4-fluoro-6-phenyl-1Hindazol-3-amines has been reported. The key intermediate is 2-(4-fluoro-6-phenyl-1H-indazol-3-ylamino) acetohydrazide (5), which has been obtained by series of reactions starting from cyclisation of 4-bromo-2, 6- difluoro benzonitrile. All the newly synthesized oxadiazole derivatives were screened for their antimicrobial activity

Published

2013-06-30

How to Cite

A KUSANUR, R. ., & MAHESH R. (2013). SYNTHESIS AND ANTI-MICROBIAL STUDY OF OXADIAZOLYL INDAZOLES: Life Science-Organic Chemistry. International Journal of Life Science and Pharma Research, 3(2), L6-L10. Retrieved from https://ijlpr.com/index.php/journal/article/view/333

Issue

Volume 3 Issue 2, April - June 2013

Section

Research Articles

Copyright (c) 2022 RAVIRAJ A KUSANUR, MAHESH R

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.