ANTIDIABETIC ACTIVITY OF KOVAI KIZHANGU CHOORANAM IN ALLOXAN INDUCED DIABETIC RATS

Pharmaceutical Science-Pharmacology

Authors

  • P. PARTHIBAN Department of Medicine, Govt. Siddha College, Arumbakkam, Chennai-600114
  • RAVIKUMAR Department of Medicine, Govt. Siddha College, Arumbakkam, Chennai-600114
  • J. ANBU Department of Pharmacology and Toxicology, School of Pharmaceutical Sciences, (VISTAS) Vels University, Pallavaram, Chennai-600117 India
  • ASHWINI ANJANA Department of Pharmacology and Toxicology, School of Pharmaceutical Sciences, (VISTAS) Vels University, Pallavaram, Chennai-600117 India

Keywords:

Kovai Kizhangu Choornam, Siddha system, Glibenclamide, Metformin, Anti-diabetic activity, Alloxan

Abstract

Kovai Kizhangu Choornam has been widely used in Siddha system of medicine for diabetes. The powder
(Kovai Kizhangu Choornam) showed a significant inhibitory effect was screened at 500 mg/kg, for the in vivo
anti-diabetic activity on alloxan induced diabetic rats. Glibenclamide: Metformin (0.5:40mg/kg) used as
reference standard. Single dose (400 mg/kg) treatment with the siddha drug Kovai Kizhangu Choornam
produced anti-hyperglycaemic effect (antidiabetic effect). The trial drug showed a significant anti-diabetic
activity and were comparable with that of standard thus validating the traditional claim of the plan

Published

2012-12-31

How to Cite

P. PARTHIBAN, RAVIKUMAR, J. ANBU, & ANJANA, A. . (2012). ANTIDIABETIC ACTIVITY OF KOVAI KIZHANGU CHOORANAM IN ALLOXAN INDUCED DIABETIC RATS: Pharmaceutical Science-Pharmacology . International Journal of Life Science and Pharma Research, 2(4), P68-P72. Retrieved from https://ijlpr.com/index.php/journal/article/view/299

Issue

Section

Research Articles