Blue Urine Following Diagnostic Hysterolaparoscopy: A Postoperative Dilemma

Authors

  • Sumbul Reema Senior Resident, Department of Obstetrics & Gynaecology, UCMS & Guru Teg Bahadur Hospital, New Delhi
  • Richa Sharma Department of Obstetrics & Gynaecology, UCMS & Guru Teg Bahadur Hospital, New Delhi

DOI:

https://doi.org/10.22376/ijlpr.v15i4.2009

Keywords:

Blue Urine, Diagnostic Hysterolaparoscopy, Chromopertubation

Abstract

Tubal factors contribute to approximately 25%–35% of female infertility, with laparoscopic chromopertubation recognized as the gold standard for evaluating tubal patency. Methylene blue is commonly used during diagnostic hysterolaparoscopy to visualize tubal flow. Although generally safe, systemic absorption followed by urinary excretion may occasionally be mistaken for a postoperative complication. Here we review a case where methylene blue appeared in urine about five hours post-procedure, prompting concerns about dye absorption and emphasizing the need to understand its pharmacokinetics and normal excretory patterns.

Author Biographies

Sumbul Reema, Senior Resident, Department of Obstetrics & Gynaecology, UCMS & Guru Teg Bahadur Hospital, New Delhi

Senior Resident, Department of Obstetrics & Gynaecology, UCMS & Guru Teg Bahadur Hospital, New Delhi

Richa Sharma, Department of Obstetrics & Gynaecology, UCMS & Guru Teg Bahadur Hospital, New Delhi

Department of Obstetrics & Gynaecology, UCMS & Guru Teg Bahadur Hospital, New Delhi

References

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Bistas E, Sanghavi DK. Methylene blue. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jun 26. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557672/

Prakash S, Saini S, Mullick P, Pawar M. Green urine: a cause for concern? J Anaesthesiol Clin Pharmacol. 2017;33(1):128–30.

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Veerendrakumar CM, Madhu YR. A rare case of delayed pulmonary oedema due to methemoglobinemia following laparoscopic chromopertubation with methylene blue. J Clin Diagn Res. 2014;8(6):OD05.

Published

2025-12-31

How to Cite

Sumbul, R., & Richa, S. (2025). Blue Urine Following Diagnostic Hysterolaparoscopy: A Postoperative Dilemma. International Journal of Life Science and Pharma Research, 15(4), 30–35. https://doi.org/10.22376/ijlpr.v15i4.2009

Issue

Section

Case Study