Phytochemical and Pharmacological Potential of Lantana Camara Linn
Pharmaceutical Science-Pharmacognosy
DOI:
https://doi.org/10.22376/ijlpr.2023.13.4.P70-P80Keywords:
Lantana camara Linn, Pharmacology, phytochemistry, oleanonic acid, Lantadene A and B, essential oilAbstract
Traditional medicine and medicinal plants, as well as their study of modern chemical principles, may lead to the creation of newer and less expensive medications. This overview incorporates all aspects of Lantana camara Linn that other papers have overlooked. Lantana camara Linn is also a widespread weed and a famous ornamental plant. It is noteworthy that plants have long been an excellent source of medicine. Lantana camara (L. camara) is well-known for its many ailments, such as cuts, inflammation, ulcers, cataract, itching, eczema, and arthritis. Various parts of the Lantana camara plant are used medicinally for colds, coughs, pox, bronchitis, and hypertension. In addition, L. camara scientifically studied various therapeutic activities such as antibacterial, antioxidant, antipyretic, larvicidal, antifungal etc. Over the past few decades, scientists and researchers worldwide have expanded their knowledge and studied the chemical composition of the entire L-plant and their medical activities. It is also known as a plant that produces essential oil, and essential oils are available in the market, known as Lantana oil. The phytoconstituents found in all portions of L. camara have been documented in various publications. Over the last few decades, scientists and researchers worldwide have thoroughly investigated the chemical content of the entire L. camara plant. The plant is widespread in Uttarakhand, Uttar Pradesh, Himachal Pradesh, and India's north-eastern provinces. This paper examined the phytochemicals found in L. camara. The review focuses on this plant's traditional usage, chemical constituents, pharmacological activity, and toxicology and other potential uses. This study aims to provide a comprehensive report on the literature on its phytochemistry and pharmacological action.
References
Ghisalberti EL. Lantana camara L. (Verbenaceae). Fitoterapia. 2000;71(5):467-86. doi: 10.1016/S0367-326X(00)00202-1.
Sankaran KV, Forest A-P, Invasive Species Network. The fact sheet is supported by the Food and Agriculture Organization of the United Nations (FAO) and the USDA Forest Service. USDA Forest Service; 2007.
Khare CP. Indian medicinal plants – an illustrated dictionary. Berlin: Springer; 2007.
Ganjewala D, . RL. Identification of Cymbopogon Species and C. flexuosus (Nees Ex. Steud) Wats Cultivars Based on Polymorphism in Esterase Isoenzymes. J Plant Sci. 2007;2(5):552-7. doi: 10.3923/jps.2007.552.557.
Barre JT, Bowden BF, Coll JC, Jesus D, La Fuente D, Janairo V, et al. A bioactive triterpenoid from Lantana camara. Phytochemistry. 1997;4:321-4.
Andersson S, Dobson HEM. Behavioural foraging responses by the butterfly Heliconius Melpomene to Lantana camara floral scent. J Chem Ecol. 2003;29(10):2303-18. doi: 10.1023/a:1026226514968, PMID 14682513.
Santos IEM. A taxonomic revision of Lantana sect. Lantana (Verbenaceae) in the Greater Antilles. Willdenowia. 2002;32(2):285-301. doi: 10.3372/wi.32.32210.
Oladoye SO. Lantana camara: phyto-constituents and antimicrobial Activity Study. PAJOLS. 2021;5(2):289-98. doi: 10.36108/pajols/1202.50.0270.
Pan WD, Mai LT, Li YJ, Xu XL, Yu DQ. Studies on the chemical constituents of the leaves of Lantana camara. Yao Xue Xue Bao. 1993;28(1):35-9. PMID 8328268.
Ganjewala D, Sam S, Hayat Khan K. Biochemical compositions and antibacterial activities of Lantana camara plants with yellow, lavender, red and white flowers. Eurasia J Biosci. 2009:69-77. doi: 10.5053/ejobios.2009.3.0.10.
Pan WD, Li YJ, Mai LT, Ohtani K, Kasai R, Tanaka O. Studies on chemical constituents of the roots of Lantana camara. Yao Xue Xue Bao. 1992;27(7):515-21. PMID 1442083.
Ayub A, Begum S, Ali SN, Ali ST, Siddiqui BS. Triterpenoids from the aerial parts of Lantana camara. J Asian Nat Prod Res. 2019;21(2):141-9. doi: 10.1080/10286020.2017.1408595, PMID 29188728.
Begum S, Zehra SQ, Hassan SI, Siddiqui BS. Noroleanane triterpenoids from the aerial parts of Lantana camara. Helv Chim Acta. 2008;91(3):460-7. doi: 10.1002/hlca.200890050.
Pan WD, Li YJ, Mai LT, Ohtani KH, Kasai RT, Tanaka O, et al. Studies on triterpenoid constituents of the roots of Lantana camara. Yao Xue Xue Bao. 1993;28(1):40-4. PMID 8328269.
Singh R, Tiwari B, Sharma U, Singh S. Chemical composition of Lantana camara fruit essential oil. Asian J Chem. 2012;24(12):5955-6.
Rana VS, Prasad D, Blazquez MA. Chemical Composition of the Leaf Oil of Lantana camara. J Essent Oil Res. 2005;17(2):198-200. doi: 10.1080/10412905.2005.9698874.
Begum S, Zehra SQ, Wahab A, Siddiqui BS. Triterpenoids secondary metabolites from Lantana CamaraLinn. Helv Chim Acta. 2006;89(9):1932-41. doi: 10.1002/hlca.200690184.
Begum S, Ayub A, Shaheen Siddiqui B, Fayyaz S, Kazi F. Nematicidal triterpenoids from Lantana camara. Chem Biodivers. 2015;12(9):1435-42. doi: 10.1002/cbdv.201400460, PMID 26363887.
Naz R, Bano A. Phytochemical screening, antioxidants and antimicrobial potential of Lantana camara in different solvents. Asian Pac J Trop Dis. 2013;3(6):480-6. doi: 10.1016/S2222-1808(13)60104-8.
Barreto F, Sousa E, Campos A, Costa J, Rodrigues F. Antibacterial activity of Lantana camara Linn and Lantana montevidensis Brig extracts from Cariri-Ceará, brazil. J Young Pharm. 2010;2(1):42-4. doi: 10.4103/0975-1483.62211, PMID 21331189.
Mansoori A, Singh N, Dubey SK, Thakur TK, Alkan N, Das SN, et al. Phytochemical characterization and assessment of crude extracts from Lantana camara L. for antioxidant and antimicrobial activity. Front Agron. 2020;2. doi: 10.3389/fagro.2020.582268.
Gidwani BK. The analgesic, anti-inflammatory and anti-hemorrhoidal activity of the aqueous extract of Lantana CamaraLinn. Res J Pharm Technol. 2009;2(2):378-81.
Shonu J, Priyank I, Amit J, Dubey BK. Pharmacognostic and phytochemical evaluation and antipyretic activity of leaves of Lantana camara Linn. Int J Biomed Adv Res. 2011;2:270-80.
Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ, Jacobson J. Helminth infections: the neglected tropical diseases. J Clin Invest. 2008;118(4):1311-21. doi: 10.1172/JCI34261, PMID 18382743.
Patel J, Deepika S, Qureshi SA. Phytochemical and anthelmintic evaluation of Lantana camara (l.) var. aculeate leaves against Pheretima Posthuma. J Glob Trends Pharm Sci. 2011.
Srivastava D, Singh P. Antifungal potential of two common weeds against plant pathogenic fungi- Alternaria ssp. Asian J Exp Biol Sci;2(3):525-8.
Tripathi S. Weed against wood-destroying fungi. Indian Forest. 2009;135(3):403-11.
Sathish R, Vyawahare B, Natarajan K. Antiulcerogenic activity of Lantana camara leaves on gastric and duodenal ulcers in experimental rats. J Ethnopharmacol. 2011;134(1):195-7. doi: 10.1016/j.jep.2010.11.049, PMID 21129476.
Thamotharan G, Sekar G, Ganesh T, Sen S, Chakraborty R, Kumar SN. Antiulcerogenic effects of Lantana camara Linn. leaves on in vivo test models in rats. Asian J Pharm Clin Res. 2010;3:57-60.
Ganesh T, Sen S, Thilagam E, Thamotharan G, Loganathan T, Chakraborty R. Pharmacognostic and anti-hyperglycemic evaluation of Lantana camara (L.) var. aculeate leaves in alloxan-induced hyperglycemic rats. Int J Res Pharm Sci. 2010;1:247-52.
Venkatachalam T. Antidiabetic activity of Lantana camara Linn fruits in normal and streptozotocin-induced diabetic rats. J Pharm Res. 1550-2;4(5).
Misra N, Sharma M, Raj K, Dangi A, Srivastava S, Misra-Bhattacharya S. Chemical constituents and anti filarial activity of Lantana camara against human lymphatic filariid Brugia malayi, and rodent filariid Acanthocheilonema vitae maintained in rodent hosts. Parasitol Res. 2007;100(3):439-48. doi: 10.1007/s00436-006-0312-y, PMID 17061115.
Pour BM, Latha LY, Sasidharan S. Cytotoxicity and oral acute toxicity studies of Lantana camara leaf extract. Molecules. 2011;16(5):3663-74. doi: 10.3390/molecules16053663, PMID 21540795.
Kumar MS, Maneemegalai S. Evaluation of the larvicidal effect of Lantana camara Linn against mosquito species Aedes aegypti and Culex quinquefasciatus. Adv Biol Res. 2008;2:39-43.
Ghodake PP, Kulkarni AS, Aloorkar NH, Osmani RA, Bhosale RR, Harkare BR. In vitro, antispasmodic activity analysis of methanolic leaves extracts of Lantana camara on excised rat ileum. J Pharmacogn Phytochem. 2013;2:66-71.
Tadesse E, Engidawork E, Nedi T, Mengistu G. Evaluation of the anti-diarrheal activity of the aqueous stem extract of Lantana camara Linn (Verbenaceae) in mice. BMC Complement Altern Med. 2017;17(1):190. doi: 10.1186/s12906-017-1696-1, PMID 28376868.
Kalita S. Phytochemical composition and in vitro hemolytic activity of Lantana camara L. (Verbenaceae) leaves. Pharmacologyonline. 2011;1:59-67.
de Mello FB, Jacobus D, de Carvalho KC, de Mello JR. Effects of Lantana camara (Verbenaceae) on rat fertility. Vet Hum Toxicol. 2003;45(1):20-3. PMID 12583691.
Naz R, Bano A. Phytochemical screening, antioxidants and antimicrobial potential of Lantana camara in different solvents. Asian Pac J Trop Dis. 2013;3(6):480-6. doi: 10.1016/S2222-1808(13)60104-8.
Mayee R, Thosar A. Evaluation of Lantana camara Linn. (Verbenaceae) for antiurolithiatic and antioxidant activities in rats. Int J Pharm Clin Res;3(1):10-4.
Nayak BS, Raju SS, Eversley M, Ramsubhag A. Evaluation of wound healing activity of Lantana camara L. - a preclinical study. Phytother Res. 2009;23(2):241-5. doi: 10.1002/ptr.2599, PMID 18844241.
Abdulla MA. Acceleration of wound healing potential by Lantana camara Leaf extracts in experimental rats. Res J Med Sci. 2009;3(2):75-9.
Ved A, Arsi T, Prakash O, Gupta A. A review on phytochemistry and pharmacological activity of Lantana camara Linn. Int J Pharm Sci Res. 2018;9(1):37-43. doi: 10.13040/IJPSR.0975-8232.9(1).37-43.
Wollenweber E, Dörr M, Muniappan R, Siems K. Flavonoid aglycones and triterpenoids from the leaf exudate of Lantana camara and Lantana montevidensis. Biochem Syst Ecol. 1997;25(3):269-70. doi: 10.1016/S0305-1978(96)00115-9.
Gotyal BS C, Srivastava S, Walia. S, K Jain and DS. Efficacy of wild sage (Lantana camara) extracts against almond moth. (Cadra cautella) in stored wheat (Triticum aestivum) seeds. Indian J Agric Sci. 2010;80(5):433-6.
Day MD. Factors influencing the biological control of lantana camarain Australia and South Africa. Proceedings of the X international symposium on biological control of weeds. 1999;4:897-908.
Ali-Emmanuel N, Moudachirou M, Akakpo JA, Quetin-Leclercq J. Treatment of bovine dermatophilosis with Senna alata, Lantana camara and Mitracarpus sabre leaf extracts. J Ethnopharmacol. 2003;86(2-3):167-71. doi: 10.1016/s0378-8741(03)00054-0, PMID 12738081.
Pasha C, Nagavalli M, Rao LV. Lantana camara for fuel ethanol production using thermotolerant yeast. Lett Appl Microbiol. 2007;44(6):666-72. doi: 10.1111/j.1472-765X.2007.02116.x, PMID 17576231.
da Silva MHL, Andrade EHA, Zoghbi MdGB, Luz AIR, da Silva JD, Maia JGS. The essential oils of Lantana camara L. occur in North Brazil. Flavour Fragr J. 1999;14(4):208-10. doi: 10.1002/(SICI)1099-1026(199907/08)14:4<208::AID-FFJ811>3.0.CO;2-F.
Banik RM, Pandey DK. Optimizing conditions for oleanolic acid extraction from Lantana camara roots using response surface methodology. Ind Crops Prod. 2008;27(3):241-8. doi: 10.1016/j.indcrop.2007.09.004.
Kuhad RC, Gupta R, Khasa YP, Singh A. Bioethanol production from Lantana camara (red sage): pretreatment, saccharification and fermentation. Bioresour Technol. 2010;101(21):8348-54. doi: 10.1016/j.biortech.2010.06.043, PMID 20584600.
Zoubiri S, Baaliouamer A. Larvicidal activity of two Algerian Verbenaceae essential oils against Culex pipiens. Vet Parasitol. 2011;181(2-4):370-3. doi: 10.1016/j.vetpar.2011.04.033, PMID 21592668.
Begum S, Zehra SQ, Wahab A, Siddiqui BS. Triterpenoids Secondary Metabolites from Lantana CamaraLinn. Helv Chim Acta. 2006;89(9):1932-41. doi: 10.1002/hlca.200690184.
Khan M, Srivastava SK, Syamasundar KV, Singh M, Naqvi AA. Chemical composition of leaf and flower essential oil of Lantana camara from India. Flavour Fragr J. 2002;17(1):75-7. doi: 10.1002/ffj.1047.
Sharma OP, Singh A, Sharma S. Levels of lantadenes, bioactive pentacyclic triterpenoids, in young and mature Lantana camara var. aculeate leaves. Fitoterapia. 2000;71(5):487-91. doi: 10.1016/S0367-326X(00)00156-8.
Sharma OP. Review of the biochemical effects of Lantana camara toxicity. Vet Hum Toxicol. 1984;26(6):488-93. PMID 6393560.
El-Banna AA, Darwish RS, Ghareeb DA, Yassin AM, Abdulmalek SA, Dawood HM. Metabolic profiling of Lantana camara L. using UPLC-MS/MS and revealing its inflammation-related targets using network pharmacology-based and molecular docking analyses. Sci Rep. 2022;12(1):14828. doi: 10.1038/s41598-022-19137-0, PMID 36050423.
Ved A, Arsi T, Prakash O, Gupta A. A review on phytochemistry and pharmacological activity of Lantana camara Linn. Int J Pharm Sci Res. 2018;9(1):37-43. doi: 10.13040/IJPSR.0975-8232.9(1).37-43.
Singh SK, Singh A, Tripathi VJ, Finzi PV. ChemInform Abstract: minor constituents of Lantana camara. ChemInform. 2010;28(39):no. doi: 10.1002/chin.199739213.
Batt AM, Ahmed MS. Chemical Components Of Lantana (Lantana Camara L) And Lemongrass (Cymbopogon Citratus “Dc.” Stapf.) Plants In Egypt. Menoufia J Agric Biotechnol. 2016;1(1):1-11. doi: 10.21608/mjab.2016.176600.
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