Recent Advancements in Transdermal Drug Delivery System: A Review
Pharmaceutical Science-Pharmaceutics
DOI:
https://doi.org/10.22376/ijlpr.2023.13.3.P24-P39Keywords:
Transdermal Delivery System, Skin, Transdermal Patch, Methods, Penetration enhancers, Market growth of TDDS.Abstract
Other non-invasive administration methods have recently become an alternative to the more conventional method of ingesting medications, which involves using a needle. The Transdermal Drug Delivery System (TDDS) is the most attractive method among them because of its low rejection rate, appreciable simplicity of administration, and superior convenience for patients. TDDS may find applications not only in the pharmaceutical industry but also in the sectors of skincare and cosmetics. This technique focuses mainly on delivering the medication in a particular area. As a result, it could reduce the formation of a local concentration of the drug and nonspecific transport to tissues that the agent does not precisely target. However, because the physicochemical characteristics of the skin translate to several obstacles and restrictions in transdermal distribution, a significant number of research is required to overcome these bottlenecks. In this study, the many different kinds of available TDDS approaches have been addressed, as well as a critical assessment of their benefits and limits, characterization methods, newly added drugs, and potential. In addition, the present study analyzes the potential of these techniques. The advancement of research into these other technologies has shown the TDDS's high level of efficiency, which has the potential to find applications in a diverse variety of industries.
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