Development of an UV spectroscopic method for Capsaicin quantification in dosage form and in a bulk formulation
Pharmaceutical Science-Pharmaceutical Analysis
DOI:
https://doi.org/10.22376/ijlpr.2023.13.3.P62-P69Keywords:
Capsaicin, UV method, Validation, Spectrophotometry, Stress degradation, Calibration curve.Abstract
A proper procedure must be created to make sure that capsaicin, whether in dosage form or in bulk, can be identified. The method development makes sure that the amount of a capsaicin can be simply determined. To determine validation parameters like accuracy, precision, LOD, LOQ, recovery study and range for capsaicin. In the present study a proper UV Spectroscopic method was developed and validated for determination of capsaicin. UV Spectrophotometric method was done at 280nm and samples were prepared with Methanol. The linearity demonstrated a correlation coefficient of 0.9922 various validation parameters like accuracy, precision, LOD, LOQ, recovery study and range were found to be within the specified range. The proposed method was simple, rapid, precise, accurate and sensitive and can be used for routine analysis of capsaicin.
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Copyright (c) 2023 Atul Baravkar, Vitthal Chopade, Sneha Dhonde, Trushali Mandhare, Pooja Kashid, Ganesh Phadtare, Jyoti Jawale, Alfa Jain, Deepali Kadam, Aditi Zagade
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