Evaluating The Efficacy of Platelet Rich Fibrin with Hydroxyapatite in The Extraction Socket of Mandibular First Molar – A Prospective Single Blind Randomized Control Study
Life Sciences-Dental
DOI:
https://doi.org/10.22376/ijlpr.2023.13.2.SP2.L151-%20L158Keywords:
Molar Teeth, Extraction, Platelet Rich Fibrin, Hydroxyapatite, Bone FormationAbstract
Tooth extraction is a common dental procedure used to manage issues such as tooth decay, fractures, periodontal disease, infections and orthodontic space creation. After a tooth is extracted, the socket typically takes about 40 days to heal. During this time, there is a natural process of bone resorption that occurs, which can make it difficult to place an implant and achieve an esthetic and functional restoration. To address this issue, a method called Platelet-Rich Fibrin (PRF) has been developed. PRF is a second-generation of autologous growth factors that is believed to accelerate wound healing and promote the formation of new bone. A recent study aimed to evaluate the effectiveness of using PRF gel with HA nanocrystals as an aid in ridge preservation for implant placement following the extraction of a mandibular first molar. Our study was a randomized controlled clinical trial that analyzed the quality of bone healing in the mandibular first molar socket using radiographic imaging at various time intervals. The aims were to evaluate the effectiveness of PRF gel with HA nanocrystals as an aid in ridge preservation for implant placement following extraction of mandibular 1st molar, a randomized controlled clinical study and to analyze the quality of bone healing in the mandibular first molar socket using RVG at various time intervals4th week and 10th week. The mean lamina dura scores at the 4th week in group I & group II 4.333 and 3.636 respectively, 10th week 3.545 and 3.091 respectively. the mean trabecular pattern in 4th week 4.364 ,3.182 respectively in 10th week 3.424 ,3.030 respectively, the mean overall density in 4th week 4.242 ,3.545 respectively in 10th week 3.485 and 2.545 respectively The results showed that the use of PRF gel with HA nanocrystals was effective in promoting bone formation and reducing bone resorption, but it is recommended that further studies are conducted to compare the efficacy of PRF with other materials and techniques. One limitation of the study was the short follow-up period of only 8 weeks. Overall, the study suggests that PRF gel with HA nanocrystals may be useful in promoting bone formation and reducing bone resorption after tooth extraction, but more research is needed to fully understand its effects.
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