Evaluation of Comparative Efficacy of Internal and External Use of Kushthadi Yoga in The Management of Ekakushtha (Psoriasis)
Life Sciences-Ayurveda
DOI:
https://doi.org/10.22376/ijlpr.2023.13.2.SP1.L30-L41Keywords:
Chakramarda, Ekakushtha, Kusthadi Yoga, PASI Scale, Psoriasis, and Yoga.Abstract
Ekakushthais one of the types of Kustha rogas. The Dosha predominance in Ekakushtha is Vata-kapaha. It exhibits clinical features of Aswedanam, Mahavastu, Ashaklopam and Kandu. On basis of clinical features Ekakushthais similar with Psoriasis by many scholars.External and internal factors, including as mild trauma, sunlight, infections, systemic medicines, and stress, can all provoke psoriasis. It can be treated by the use of topical, systemic antifungals, or corticosteroids as per modern science. Longterm use of these drugs may produce adverse effects or there may be more chances of recurrences after the stoppage of treatment. Hence there is need to study to study the Shodhana and Shaman chikitsa mentioned in Ayurveda whichare considered the most effective in twakvikar. The aim and objective of this study is to compare the effects of Kusthadi yoga and a placebo capsule in the treatment of Ekakushta (Psoriasis). A total of 40 patients were enrolled, and they were divided into 2 groups at random. For 30 days, Group A received Kushthadi Ointment and Kushthadi Capsule, whereas Group B received Kushthadi Ointment and Palcebo capsule. Patients were assessed for Kandu and PASI score on 0, 15thand 30th day. Both groups showed significant improvement in Kandu and PASI scale after treatment. But improvement was observed in a greater number of patients in group A treated with Kushthadi Ointmentand Kushthadi Capsule.The improvement was observed due to Kushthaghna, Kandughna, Krumighna, Tridoshshamaka, Raktavikarnashak,Rasayana andVirechakaproperties of ingredients of Kushthadi yoga.It possesses antipsoriatic, antiinflammatory, antipruritic, antibacterial and antioxidants which helps in reducing symptoms. Kushthadi Yoga is effective in the management of Ekakushtha and ifit is given internally along with local application then it shows better results. Keywords: , ,, ,
References
Boon NA, Nicki R. College. In: Walker BR, editor. Davidson’s principles and practice of medicine. 22nd ed. New York: Churchill Livingstone Elsevier Publication; 2014.
nd Part, 28thChapter. Page No. 1252.
Mythrey RC, Madhu HM, Hegde G. Conceptual analysis of Dadru vis-à-vis tinea, Journal Of Biological And Scientific Opinion. Sep-Oct 2014;2(5), Pg No. 332-334.
Marks R. Roxburgh’s common skin diseases. 16th ed, ELBS With Chapman And Hall, London [Chapter]. Vol. 1; 1993. p. 1.
Abhilash PS, Ittoop JA, Sailekha P. Efficacy of Shirish Twaklepa in the management of Dadru. Int Ayurvedic Med J. Aug 2015;3(8), Pg No. 2265-2269.).
Thakur SK, Deshmukh UP, Varshney J. ’Efficacy Of DadruharLepa In Dadru (Tinea) – A Case Study’, world Journal Of Pharmaceutical And Medical Research. Feb 2018;4(3), Pg No. 293-296.
Jadavjitrikamjiacharya CS (Ayurveda Dipika Commentary Of Chakrapanidatta Revised By CharakaAnd Dridabala)., Editor. Varanasi: Chaukhamba Sanskrit Samsthana; Chikitsasthana. 5th ed. 2011;7/21.Page No.451-452.
Sharma RK, Dash B, Editos A, Chikitsasthana, Chapter 7. Verse21,Varanasi:Choukhambakrishnadasacademy,2009:Pp–738.
Sharmap. V, Chapter 5, Verse 9. In: Susruta S, editor. Nidanasthana. Varanasi: ChoukhambaKrishnadas Academy; 2010: Pp –824.
Pasrichaj. S,Guptar,Illustrated textbook of dermatology, Jayshree brothers publications, edition; 1996. P. 132Pp-157.
Institute For Health Metrics And Evaluation (IHME). Global burden of disease Study 2010: results by cause 1990-2010. Seattle: IHME; 2012.
Boehncke WH, Schön MP. Psoriasis. Lancet. 2015;386(9997):983-94. doi: 10.1016/S0140-6736(14)61909-7, PMID 26025581.
Lo KK, Ho LY. Psoriasis: handbook of dermatology and venereology. 2nd ed. Hong Kong: Social Hygiene Service, Department Of Health; 1997.
Gibbs S. Skin disease and socioeconomic conditions in rural Africa: Tanzania. Int J Dermatol. 1996;35(9):633-9. doi: 10.1111/j.1365-4362.1996.tb03687.x, PMID 8876289.
Danielsen K, Olsen AO, Wilsgaard T, Furberg AS. Is the prevalence of psoriasis increasing? A 30–year follow-up of A population–based cohort. Br J Dermatol. 2013;168(6):1303-10. doi: 10.1111/bjd.12230, PMID 23374051.
Global report on PSORIASIS -World health organization. ISBN 978 92 4 156518 9.
Http://Apps.Who.Int/Iris/Bitstream/10665/204417/1/9789241565189_Eng.Pdf.Psoriasis.
Farber EM, Nall ML, Watson W. Natural history of psoriasis in 61 twin pairs. Arch Dermatol. 1974;109(2):207-11. doi: 10.1001/archderm.1974.01630020023005, PMID 4814926.
Shukla V, Tripthi RV, Chapter 7. Delhi: Chukhambasanskritapratisthana, verse. In: Editors Charaka Samhita, Chikitsasthan. Vol. 139; 2010; No.-186.
Shukla V, Tripthi RV, Chapter 7. Verse. In: Editors Charaka Samhita, Chikitsasthan, Delhi: Chukhambasanskritapratisthana. Vol. 139; 2010; No.-190.
Jadavjitrikamjiacharya CS (Ayurveda Dipika Commentary Of Chakrapanidatta Revised By CharakaAnd Dridabala)., Editor. Varanasi: Chaukhamba Sanskrit Samsthana; Chikitsasthana. 5th ed. 2011;7/21.Page No.451-452.
World Health Organization. Global report on psoriasis. Global report on psoriasis 2016. In:.
Vijayalalshmi A Et Al. Anti-psoriatic activity of flavonoids from Cassia Tora Leaves using the rat ultraviolet B Ray photodermatitis model, Revistabrasileira de Farmacognosia,Volume. On 29.04.2019. 2014, Page No.. 322-329;24(3, May-Jun):10am.
Singhal M, Kansara N. Cassia tora Linn Cream Inhibits Ultraviolet-B-Induced Psoriasis in Rats. ISRN Dermatol. 2012;2012:346510. doi: 10.5402/2012/346510. PMID 22536527.
Bhavamishra, Nighantu B. Hindi commentary by K.C.Chunekar. 1sted. Varanasi: Chaukhumbha Bharathi Academy; 2002, P.-984.
Ali MdA. In-vitro antibacterial activity of leaf and root extract of cassia fistula Dinajpur Med. Clg J. 2010;3:10-3.
Bhavamishra, Nighantu B. Hindi commentary by K.C.Chunekar. 1sted. Varanasi: Chaukhumbha Bharathi Academy; 2002, Tpg-974.
Shukla V, Tripathi RD, editors. Charak Samhita, Chikitsasthana, Chaptar 7, Verse 21, Delhi: Chukhamba Sanskrit Pratishthan, 2010 ;Pp-184.
Sharma PV, editor, Chapter 5. Verse5. In: Shush rut Samhita, Nidansthan. Varanasi: Chaukhamba Vishvabharti Publication; 2005;Pp-37.
Tripathi B, editor, Chapter 14. Verse 3-4 Delhi: Chukhamba Sanskrit Pratishthan. In: Ashtanga Hriday, Nidansthan; 2015,Pp-527.
Agnivesha CS, Vyakya CCHindi. By Dr. Brahmanand. Tripati, Choukambha Vidya bhavan Varanasi. 1st ed, 1962. Chapter C 16. Version 72. Page. Vol. 603.
Hróbjartsson A, Gøtzsche PC. Is the placebo powerless? Update of a systematic review with 52 new randomized trials comparing placebo with no treatment. J Intern Med. 2004;256(2):91-100. doi: 10.1111/j.1365-2796.2004.01355.x. PMID 15257721.
Ellis CN, Barker JN, Haig AE, Parker CA, Daly S, Jayawardene DA et al. Placebo response in two long-term randomized psoriasis studies that were negative for rosiglitazone. Am J Clin Dermatol. 2007;8(2):93-102. doi: 10.2165/00128071-200708020-00005, PMID 17428114.
Published
How to Cite
Issue
Section
Copyright (c) 2023 Ashish U. Nimbhorkar, Sadhana Misar Wajpeyi
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
