PHARMACOKINETIC AND PHARMACODYNAMIC INTERACTION BETWEEN LUMIRACOXIB AND FLUVASTATIN

Pharmaceutical Science-Pharmacology

Authors

  • JAYARAMAN ANBU Department of Pharmacology and Toxicology, School of Pharmaceutical Sciences, (VISTAS) Vels University, Pallavaram, Chennai-600117 India
  • ASHWINI ANJANA Department of Pharmacology and Toxicology, School of Pharmaceutical Sciences, (VISTAS) Vels University, Pallavaram, Chennai-600117 India
  • C. ROOSEWELT Department of Pharmacology and Toxicology, School of Pharmaceutical Sciences, (VISTAS) Vels University, Pallavaram, Chennai-600117 India
  • G. SRINIVASA RAO Department of Pharmacology and Toxicology, School of Pharmaceutical Sciences, (VISTAS) Vels University, Pallavaram, Chennai-600117 India
  • R. SATHISH Department of Toxicology, NIS, Tambaram, Chennai-600044, India

Keywords:

Lumiracoxib, Fluvastatin, COX-2 inhibitors, Rheumatoid arthritis, Hypolipidemic, ASHWINI ANJANA

Abstract

The present study was carried out to investigate the pharmacokinetics and pharmacodynamic interaction
between Lumiracoxib (20mg/kg p.o.) and Fluvastatin (5mg/kg p.o.) alone and their combination in rats by
open labeled parallel study design. The animals were maintained on a standard laboratory conditions and
were divided into 3 and 6 groups for Pharmacokinetic and Pharmacodynamic studies respectively

Published

2012-06-30

How to Cite

ANBU, J., ANJANA, A. ., C. ROOSEWELT, RAO, G. S. ., & R. SATHISH. (2012). PHARMACOKINETIC AND PHARMACODYNAMIC INTERACTION BETWEEN LUMIRACOXIB AND FLUVASTATIN: Pharmaceutical Science-Pharmacology. International Journal of Life Science and Pharma Research, 2(2), P42-P50. Retrieved from https://ijlpr.com/index.php/journal/article/view/151

Issue

Volume 2 Issue 2, April - June 2012

Section

Research Articles

Copyright (c) 2022 JAYARAMAN ANBU, ASHWINI ANJANA, C. ROOSEWELT, G. SRINIVASA RAO, R. SATHISH

Creative Commons License

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