EVALUATION OF EFFECTS OF LEAD, ALCOHOL AND VITAMIN E ON LIPID PEROXIDATION ON BRAIN TISSUE

Pharmaceutical Science-Clinical and Hospital Pharmacy

Authors

  • DR.ANUSUYA.M.R Associate Professor, Department of Biochemistry, Kempegowda Institute of Medical Sciences, Banashankari 2nd Stage, Bangalore-560070
  • DR.KIRAN.B Head of the Department, PG Department of Biosciences, CMR Institute of Management Studies (Autonomous) C.A. #2, 3rd ‘C’ Cross, 6th ‘A’ Main, HRBR layout, 2nd Block, Kalyana Nagar, Bangalore -560043, Karnataka State, India

Keywords:

lipid peroxidation, Lead, Alcohol, Vitamin E, Brain tissue

Abstract

In vitro evaluation of lipid peroxidation activity on brain tissue of rats treated with lead, alcohol and vitamin E individually and in combination were evaluated at two, four and eight weeks of treatment . In eight weeks of treatment, maximum effect of lead and alcohol was recorded and the MDA(Malondialdehyde) value was58.74nmol/gram of brain tissue in lead, 69.74nmol/gram in alcohol and 86.68nmol/gram in lead with alcohol treated rats. In Vitamin treated rats, the MBA value was 21.32nmol/gram and 28.08nmol/gram in lead with vitamin E treated rats and in alcohol with vitamin E treated rats, the MDA value was 38.06nmol/gram of brain tissue. In combination of lead, alcohol and vitamin E, the MDA value was 39.60nmol/gram tissue

Published

2012-06-30

How to Cite

DR.ANUSUYA.M.R, & DR.KIRAN.B. (2012). EVALUATION OF EFFECTS OF LEAD, ALCOHOL AND VITAMIN E ON LIPID PEROXIDATION ON BRAIN TISSUE: Pharmaceutical Science-Clinical and Hospital Pharmacy. International Journal of Life Science and Pharma Research, 2(2), P37-P41. Retrieved from https://ijlpr.com/index.php/journal/article/view/149

Issue

Volume 2 Issue 2, April - June 2012

Section

Research Articles

Copyright (c) 2022 DR.ANUSUYA.M.R, DR.KIRAN.B

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