International Journal of Life science and Pharma Reviews (IJLPR)  
International Journal of Life science and Pharma Research (IJLPR)
Pharmaceutical Sciences
Volume 2 Issue 2, April - June 2012    Pages:42-50
Pharmacokinetic And Pharmacodynamic Interaction Between Lumiracoxib And Fluvastatin

Jayaraman Anbu,Ashwini Anjana,C. Roosewelt,G. SrinivasaRao And R. Sathish
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DOI: DOI not available
The present study was carried out to investigate the pharmacokinetics and pharmacodynamic interaction between Lumiracoxib (20mg/kg p.o.) and Fluvastatin (5mg/kg p.o.) alone and their combination in rats by open labeled parallel study design. The animals were maintained on a standard laboratory conditions and were divided into 3 and 6 groups for Pharmacokinetic and Pharmacodynamic studies respectively.
Keywords: Lumiracoxib, Fluvastatin, COX-2 inhibitors, Rheumatoid arthritis, Hypolipidemic
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