International Journal of Life science and Pharma Reviews (IJLPR)  
International Journal of Life science and Pharma Research (IJLPR)
Pharmaceutical Sciences
Volume 2 Issue 2, April - June 2012    Pages:37-41
Evaluation Of Effects Of Lead, Alcohol And Vitamin E On Lipid Peroxidation On Brain Tissue

Dr. Anusuya.M.R And Dr.Kiran B.
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DOI: DOI not available
In vitro evaluation of lipid peroxidation activity on brain tissue of rats treated with lead, alcohol and vitamin E individually and in combination were evaluated at two, four and eight weeks of treatment . In eight weeks of treatment, maximum effect of lead and alcohol was recorded and the MDA(Malondialdehyde) value was58.74nmol/gram of brain tissue in lead, 69.74nmol/gram in alcohol and 86.68nmol/gram in lead with alcohol treated rats. In Vitamin treated rats, the MBA value was 21.32nmol/gram and 28.08nmol/gram in lead with vitamin E treated rats and in alcohol with vitamin E treated rats, the MDA value was 38.06nmol/gram of brain tissue. In combination of lead, alcohol and vitamin E, the MDA value was 39.60nmol/gram tissue.
Keywords: lipid peroxidation, Lead, Alcohol, Vitamin E, Brain tissue
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