International Journal of Life science and Pharma Reviews (IJLPR)  
International Journal of Life science and Pharma Research (IJLPR)
Pharmaceutical Sciences
Volume 2 Issue 1, January - March 2012    Pages:10-12
Evaluation Of Anthelmintic Activity Of Carica PapayaLatex Using Pheritima Posthuma

Lakshmi Kanta Kanthal, Prasenjit Mondal, Somnath De, SomaJana, S. Aneela And K. Satyavathi
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DOI: DOI not available
The aim of present study is to evaluate Anthelmintic potential of latex of Carica papaya using Pheretima posthuma as test worms. Various concentrations (100%, 50%, and 20%) of Carica papaya latex were tested in the assay, which involved determination of time of paralysis (P) and time of death (D) of the worms. It show shortest time of paralysis (P=24.5 min) and death (D=56min) in 100% concentration, while the time of paralysis and death will increase in 50% concentration (P=28min&D=64min) and in 20% concentration (P=34min&D=74min) respectively as compare to Piperazine citrate (10mg/ml) used as standard reference (P= 24 min& D= 54) and distilled water as control. The results of present study indicated that the latex of Carica papaya showed significantly demonstrated paralysis, and also caused death of worms especially at higher concentration as compared to standard reference Piperazine citrate and control. From the result it is conclude that the latex of Carica papaya showed significant Anthelmintic activity.
Keywords: Pheretima posthuma, Anthelmintic, Carica papaya latex, Piperazine citrate.
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