International Journal of Life science and Pharma Reviews (IJLPR)  
   
 
International Journal of Life science and Pharma Research (IJLPR)
Pharmaceutical Sciences
Volume 1 Issue 1, October - December 2011    Pages:21-27
Evaluation of antiperoxidative potential of water extract of spirulina platensis on busulfan-induced lipid peroxidation using 4-hydroxy nonenal and nitric oxide as model markers

Supratim Ray
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DOI: DOI not available
Abstract:
This in vitro study was designed to evaluate free radical scavenging activity of water extract of Spirulina platensis on busulfan-induced lipid peroxidation using 4-hydroxy nonenal and nitric oxide as model markers. In this study goat liver has been used as liver source. The results suggest that busulfan could induce lipid peroxidation to a significant extent and it was also found that water extract of the Spirulina platensis has the ability to suppress the busulfan-induced toxicity. 
Keywords: Busulfan, Spirulina platensis, lipid peroxidation, 4-hydroxy-2-nonenal, nitric oxide
 
 
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