International Journal of Life science and Pharma Reviews (IJLPR)  
   
 
International Journal of Life science and Pharma Research (IJLPR)
Life Science
Volume 8 Issue 3, July-September 2018    Pages:39-45
COMPARISON EFFECTIVENESS OF MBSR AND CBT ON INTERLEUKIN 6 AND OXIDATIVE STRESS IN HYPERTENSIVE PATIENTS

BEHROOZ BIRASHK, FARSHAD SHEYBANI*, BANAFSHEH GHARRAEE, MOHAMADREZA PIRMORADI, SHOKOUFEH HAJSADEGHI
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DOI: http://dx.doi.org/10.22376/ijpbs/lpr.2018.8.3.L39-45
Abstract:
Cardiovascular diseases are the leading cause of death in developing countries. Research has shown that the level of oxidative stress and interleukin 6 (IL-6) is higher in individuals with hypertension than individuals with normal blood pressure. Therefore, the aim of the present randomized clinical trial study was to compare the effectiveness of mindfulness-based stress reduction (MBSR) and cognitive-behavioral therapy (CBT) on oxidative stress and interleukin 6. Sixty patients with primary hypertension were divided into two intervention groups (MBSR and CBT) and one control group. Oxidative stress and IL-6 were measured by prooxidant-antioxidant balance (PAB) and ELISA method (Biovendor kit), respectively. Data analysis was carried out using ANOVA and MANCOVA in SPSS Ver.19. The results showed that MBSR significantly reduced oxidative stress. Also, MBSR and CBT significantly reduced IL-6 levels.
Keywords: Hypertension; Interleukin 6; Oxidative Stress; Mindfulness-Based Stress Reduction; Cognitive- Behavioral Stress Management
 
 
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