International Journal of Life science and Pharma Reviews (IJLPR)  
   
 
International Journal of Life science and Pharma Research (IJLPR)
Life Science
Volume 1 Issue 1, October - December 2011    Pages:71-76
Synthesis and Biological Studies of Trihydro Pyrido [2, 3-D] Pyrimidines 6 - Carbonitrile

Parthiv. K. Chaudhari
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DOI: DOI not available
Abstract:
The synthesis of 5-amino-4-aryl-7-oxo-2-mercato-4,8,4a-trihydro pyrido [2,3-d]pyrimidines-6-carbonitrile (VIIIa-m) have been undertaken by the condensation of 4-amino -5-cyano-6-aryl-2-mercato-5,6-dihydro pyrimidines with ethylcyanoacetate. The constitution of the products has been delineated by elemental analyses IR, PMR and mass spectral data.
Keywords: Trihydro pyrido [2, 3-d] pyrimidines-6-carbonitrile, Multicomponent reaction, cyclocondensation,antibacterial activity, antifungal activity, Therapeutic agents.
 
 
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