International Journal of Life science and Pharma Reviews (IJLPR)  
   
 
International Journal of Life science and Pharma Research (IJLPR)
Life Science
Volume 3 Issue 2, April - June 2013    Pages:06-10
SYNTHESIS AND ANTI-MICROBIAL STUDY OF OXADIAZOLYL INDAZOLES

Raviraj A KusanurA, Mahesh RA
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DOI: DOI not available
Abstract:
A rapid and efficient synthesis of substituted N-[(1,3,4-oxadiazol-2-yl)methyl]-4-fluoro-6-phenyl-1H-indazol-3-amines has been reported. The key intermediate is 2-(4-fluoro-6-phenyl-1H-indazol-3-ylamino) acetohydrazide (5), which has been obtained by series of reactions starting from cyclisation of 4-bromo-2, 6-difluoro benzonitrile. All the newly synthesized oxadiazole derivatives were screened for their antimicrobial activity.
Keywords: 3-Aminoindazole, Suzuki reaction, Oxadiazoles, anti-microbial activity.
 
 
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